Dodgers at Padres Prediction: Odds, expert picks, starting pitchers, betting trends and stats for June 11

It's Wednesday, June 11 and the Dodgers (40-28) are in San Diego to take on the Padres (38-28). Ben Casparius is slated to take the mound for Los Angeles against Randy Vásquez for San Diego.

The Padres leveled the series last night with an 11-1 win. Dyland Cease was dominant on the mound yesterday. He pitched 7.0 shutout innings with 11 strikeouts on just three hits.

Let's dive into the matchup and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

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Game details & how to watch Dodgers at Padres

• Date: Wednesday, June 11, 2025
• Time: 4:10PM EST
• Site: Petco Park
• City: San Diego, CA
• Network/Streaming: Padres Television Network, SportsNet LA

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Dodgers at the Padres

The latest odds as of Wednesday:

• Moneyline: Dodgers (-143), Padres (+120)
• Spread:  Dodgers -1.5
• Total: 9.0 runs

Probable starting pitchers for Dodgers at Padres

• Pitching matchup for June 11, 2025: Ben Casparius vs. Randy Vásquez
  
  • Dodgers: Ben Casparius, (4-1, 2.93 ERA)
    Last outing (St. Louis Cardinals, 6/7): 1.0 Innings Pitched, 2 Earned Runs Allowed, 5 Hits Allowed, 0 Walks, and 0 Strikeouts
  • Padres: Randy Vásquez, (3-4, 3.70 ERA)
    Last outing (Milwaukee Brewers, 6/6): 4.2 Innings Pitched, 0 Earned Runs Allowed, 2 Hits Allowed, 4 Walks, and 2 Strikeouts

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Top betting trends & insights to know ahead of Dodgers at Padres

• On the road the Dodgers have won 9 of the last 14 games they have played following a defeat
• 5 of the Dodgers' last 6 road trips to the Padres have gone over the Total
• The Dodgers have failed to cover the Run Line in 9 of their last 10 games

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for tonight’s game between the Dodgers and the Padres

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Wednesday's game between the Dodgers and the Padres:

• Moneyline: NBC Sports Bet is recommending a play on the Los Angeles Dodgers on the Moneyline.
• Spread: NBC Sports Bet is leaning towards a play ATS on the San Diego Padres at +1.5.
• Total: NBC Sports Bet is recommending a play on the over on the Game Total of 9.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC

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• Jay Croucher (@croucherJD)
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