Giants at Padres Prediction: Odds, expert picks, starting pitchers, betting trends and stats for April 30

Its Wednesday, April 30 and the Giants (19-11) are in San Diego wrapping up a two-game series against the Padres (18-11).

Landen Roupp is slated to take the mound for San Francisco against Michael King for San Diego.

The Padres won last night, 7-4. Xander Bogaerts went 2-4 and drove in three to lead San Diego to their 18th win of the season. Nick Pivetta gave up three runs in 5.1 innings to earn his fifth win of the season.

Lets dive into the matchup and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

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Game details & how to watch Giants at Padres

• Date: Wednesday, April 30, 2025
• Time: 4:10PM EST
• Site: Petco Park
• City: San Diego, CA
• Network/Streaming: NBCSBA, SDPA

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Giants at the Padres

The latest odds as of Wednesday:

• Moneyline: Giants (+114), Padres (-135)
• Spread:  Padres -1.5
• Total: 7.0 runs

Probable starting pitchers for Giants at Padres

• Pitching matchup for April 30, 2025: Landen Roupp vs. Michael King
  
  • Giants: Landen Roupp (2-1, 4.56 ERA)
    Last outing: 4/24 vs. Milwaukee - 3.2IP, 3ER, 6H, 3BB, 2Ks
  • Padres: Michael King (3-1, 2.18 ERA)
    Last outing: 4/25 vs. Tampa Bay - 5IP, 0ER, 4H, 1BB, 9Ks

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Top betting trends & insights to know ahead of Giants at Padres

• The Padres have won 4 of their last 5 games at home against NL West teams
• Manny Machado went 2-4 last night but is just 4-22 in his last 6 games
• The Giants have failed to cover the Run Line in 6 of their last 7 road games
• Willy Adames has hits in 6 of his last 7 games (7-25)

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for today’s game between the Giants and the Padres

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Wednesday's game between the Giants and the Padres:

• Moneyline: NBC Sports Bet is recommending a play on the San Diego Padres on the Moneyline.
• Spread: NBC Sports Bet is leaning towards a play ATS on the San Francisco Giants at +1.5.
• Total: NBC Sports Bet is recommending a play on the over on the Game Total of 7.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC

Follow our experts on socials to keep up with all the latest content from the staff:

• Jay Croucher (@croucherJD)
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• Vaughn Dalzell (@VmoneySports)
• Brad Thomas (@MrBradThomas)