Marlins at Pirates Prediction: Odds, expert picks, starting pitchers, betting trends and stats for June 10

It's Tuesday, June 10 and the Marlins (24-40) are in Pittsburgh to take on the Pirates (27-40). Sandy Alcantara is slated to take the mound for Miami against Mitch Keller for Pittsburgh.

The Pirates have won a season-high four-straight games after taking Game 1 against the Marlins, 10-3, after sweeping the Phillies. Miami has lost two straight and six of the previous seven games.

Let's dive into the matchup and find a sweat or two. We’ve got all the info and analysis you need to know ahead of the game, including the latest info on how to catch first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

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Game details & how to watch Marlins at Pirates

• Date: Tuesday, June 10, 2025
• Time: 6:40PM EST
• Site: PNC Park
• City: Pittsburgh, PA
• Network/Streaming: FDSNFL, SNP

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Marlins at the Pirates

The latest odds as of Tuesday:

• Moneyline: Marlins (+109), Pirates (-131)
• Spread:  Pirates -1.5
• Total: 8.0 runs

Probable starting pitchers for Marlins at Pirates

• Pitching matchup for June 10, 2025: Sandy Alcantara vs. Mitch Keller
  
  • Marlins: Sandy Alcantara, (2-7, 7.90 ERA)
    Last outing: 6.0 Innings Pitched, 2 Earned Runs Allowed, 4 Hits Allowed, 1 Walks, and 4 Strikeouts
  • Pirates: Mitch Keller, (1-8, 4.13 ERA)
    Last outing: 6.1 Innings Pitched, 6 Earned Runs Allowed, 8 Hits Allowed, 1 Walks, and 5 Strikeouts

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Expert picks & predictions for tonight’s game between the Marlins and the Pirates

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Tuesday’s game between the Marlins and the Pirates:

• Moneyline: NBC Sports Bet is recommending a play on the Pittsburgh Pirates on the Moneyline.
• Spread: NBC Sports Bet is leaning towards a play ATS on the Miami Marlins at +1.5.
• Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC.

Top betting trends & insights to know ahead of Marlins at Pirates

• The Pirates have won 5 straight home games against the Marlins
• In his last 5 starts on the mound the Pirates pitcher Mitch Keller has an ERA of 4.48
• The Marlins have covered in 4 of their last 5 on the road, profiting 1.84 units

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

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• Jay Croucher (@croucherJD)
• Drew Dinsick (@whale_capper)
• Vaughn Dalzell (@VmoneySports)
• Brad Thomas (@MrBradThomas)