Orioles at Twins Prediction: Odds, expert picks, starting pitchers, betting trends and stats for May 7

Its Wednesday, May 7 and the Orioles (13-21) are in Minneapolis to take on the Twins (16-20). Charlie Morton is slated to take the mound for Baltimore against Simeon Woods Richardson for Minnesota.

After a 9-1 loss in the series' first game, the Orioles have now lost three games in a row.

Cade Povich gave up five earned runs off six hits in 6.0 innings for the Orioles. Pablo Lopez was great for the Twins. He struck out 11 batters and only gave up two hits in 5.0 innings.

Lets dive into the matchup and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.

Game details & how to watch Orioles at Twins

• Date: Wednesday, May 7, 2025
• Time: 7:40PM EST
• Site: Target Field
• City: Minneapolis, MN
• Network/Streaming: Twins.TV, MASN, MASN+

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Orioles at the Twins

The latest odds as of Wednesday:

• Moneyline: Orioles (+115), Twins (-135)
• Spread:  Twins -1.5
• Total: 9.0 runs

Probable starting pitchers for Orioles at Twins

• Pitching matchup for May 7, 2025: Charlie Morton vs. Simeon Woods Richardson
  
  • Orioles: Charlie Morton, (0-6, 9.76 ERA)
    Last outing (Kansas City Royals, 5/4): 1.0 Innings Pitched, 2 Earned Runs Allowed, 3 Hits Allowed, 0 Walks, and 0 Strikeouts
  • Twins: Simeon Woods Richardson, (2-2, 4.03 ERA)
    Last outing (Cleveland Guardians, 5/1): 4.2 Innings Pitched, 2 Earned Runs Allowed, 2 Hits Allowed, 5 Walks, and 4 Strikeouts

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Top betting trends & insights to know ahead of Orioles at Twins

• The Twins have won their last 3 home games, while the Orioles have lost 3 straight on the road
• The Orioles' last 6 road games have stayed under the Total
• The Twins are up 3.75 units on the Run Line in their last 5 games at Target Field

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for tonight’s game between the Orioles and the Twins

Rotoworld Best Bet

Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700.

Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Wednesday's game between the Orioles and the Twins:

• Moneyline: NBC Sports Bet is recommending a play on the Minnesota Twins on the Moneyline.
• Spread: NBC Sports Bet is leaning towards a play ATS on the Baltimore Orioles at +1.5.
• Total: NBC Sports Bet is staying away from a play on the Game Total of 9.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC

Follow our experts on socials to keep up with all the latest content from the staff:

• Jay Croucher (@croucherJD)
• Drew Dinsick (@whale_capper)
• Vaughn Dalzell (@VmoneySports)
• Brad Thomas (@MrBradThomas)