Rays at Red Sox Prediction: Odds, expert picks, starting pitchers, betting trends and stats for June 10

It's Tuesday, June 10 and the Rays (36-30) are in Boston to take on the Red Sox (32-36). Ryan Pepiot is slated to take the mound for Tampa Bay against Lucas Giolito for Boston.

Tampa Bay took Game 1 of the series in extra innings, 10-8, yesterday behind two runs in the top of the 11th. The Rays spoiled the debut of the No. 1 prospect in baseball, Roman Anthony. The rookie went 0-for-4, but had a clutch at-bat bringing in a run during the bottom of the 9th inning off a ground out fielders choice.

Let's dive into the matchup and find a sweat or two. We’ve got all the info and analysis you need to know ahead of the game, including the latest info on how to catch first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

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Game details & how to watch Rays at Red Sox

• Date: Tuesday, June 10, 2025
• Time: 7:10PM EST
• Site: Fenway Park
• City: Boston, MA
• Network/Streaming: FDSNSUN, NESN

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Rays at the Red Sox

The latest odds as of Tuesday:

• Moneyline: Rays (-115), Red Sox (-105)
• Spread:  Rays -1.5
• Total: 9.0 runs

Probable starting pitchers for Rays at Red Sox

• Pitching matchup for June 10, 2025: Ryan Pepiot vs. Lucas Giolito
  
  • Rays: Ryan Pepiot, (3-5, 3.20 ERA)
    Last outing: 6.0 Innings Pitched, 2 Earned Runs Allowed, 3 Hits Allowed, 2 Walks, and 8 Strikeouts
  • Red Sox: Lucas Giolito, (1-1, 6.42 ERA)
    Last outing: 1.2 Innings Pitched, 7 Earned Runs Allowed, 8 Hits Allowed, 1 Walk, and 1 Strikeout

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Expert picks & predictions for tonight’s game between the Rays and the Red Sox

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Tuesday’s game between the Rays and the Red Sox:

• Moneyline: NBC Sports Bet is recommending a play on the Tampa Bay Rays on the Moneyline.
• Spread: NBC Sports Bet is leaning towards a play ATS on the Boston Red Sox at +1.5.
• Total: NBC Sports Bet is recommending a play on the over on the Game Total of 9.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC.

Top betting trends & insights to know ahead of Rays at Red Sox

• The Rays have won four of five games at divisional opponents
• The Over is 4-1 in the Red Sox's last five divisional matchups
• The Rays have covered the Run Line in seven of their last nine road games

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

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• Jay Croucher (@croucherJD)
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• Vaughn Dalzell (@VmoneySports)
• Brad Thomas (@MrBradThomas)